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Specifically, whereas NF-B subunits have already been reported to sex møter twitter demonstrate features of tumour suppressors knockout mice created normally without results on B-cell maturation but perform display some immunological flaws, including decreased B-cell proliferation and activation, irregular germinal centres and reduced quantity of marginal zone.
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The REL gene, encoding the NF-B subunit c-Rel, is generally amplified in B-cell lymphoma and functions being a tumour-promoting transcription factor.
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